Challenges of starting treatment protocols for acute lymphoblastic leukaemia in a low‐income setting — the Blantyre experience

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Osteonecrosis following treatment for childhood acute lymphoblastic leukaemia: The Southampton Children’s Hospital experience

Purpose To determine the prevalence of osteonecrosis (ON) in children following treatment of acute lymphoblastic leukaemia (ALL), characterise these cases and review treatment methods. Methods All children diagnosed and treated for ALL between 01 January 2003 and 31 December 2013 at our centre were retrospectively reviewed. Logistic regression was used to investigate risk factors for ON occur...

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Acute lymphoblastic leukaemia (ALL) is a malignant transformation of a clone of cells from lymphoid progenitor cells. The majority of cases are of B-cell origin but it can also arise from T-cell precursors. Lymphoid precursors proliferate and replace the normal cells of the bone marrow and blasts spill into the peripheral circulation. It can be distinguished from other malignancies of lymphoid ...

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Acute lymphoblastic leukaemia.

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2020

ISSN: 0007-1048,1365-2141

DOI: 10.1111/bjh.17040